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Lauren McGee

About Lauren McGee

  • Lauren McGee

    Undergraduate university: Hanover College (B.S. in biology)
  • Thesis: Students choose their thesis lab/mentor in March of their first academic year.
  • Experience: Prior to graduation, Lauren spent two summers working at Eli Lilly and Company in the department of Translational Medicine and one summer working with Dr. Mindy Davis at the NIH National Center for Advancing Translational Sciences (NCATS). She joined Dr. Marc Ferrer’s group as a post-baccalaureate fellow and subsequently served as a staff biologist. One of her projects focused on developing a high-throughput screening assay to determine small-molecule inhibitors for exosome biogenesis and secretion in castration-resistant prostate cancer cell lines and inhibitors for exosome uptake by adipocytes, with the goal of targeting a path of metastasis. Another project she works on is focused on developing 3-D models (layered and spheroid) for high-throughput screening of breast and ovarian cancers that will better mimic the tumor microenvironment and increase the accuracy of screening.
  • Hometown: Fishers, Indiana
  • Hobbies: Running, cross-stitching and baking
PUBLICATIONS

To view Lauren’s LinkedIn profile, click here, and to view her Google Scholar page, click here.

Lal-Nag M, McGee L, Guha R, Lengyel E, Kenny HA, Ferrer M. 2017. A high-throughput screening model of the tumor microenvironment for ovarian cancer cell growth. SLAS Discov 22(5):494–506.

David MI, Pragani R, Fox JT, Shen M, Parmar K, Gaudiano EF, Liu L, Tanega C, McGee L, Hall MD, McKnight C, Shinn P, Nelson H, Chattopadhyay D, D’Andrea AD, Auld DS, DeLucas LJ, Li Z, Boxer MB, Simeonov A. 2016. Small molecule inhibition of the ubiquitin-specific protease USP2 accelerates cyclin D1 degradation and leads to cell cycle arrest in colorectal cancer and mantle cell lymphoma models. J Biol Chem 291:24628–24640.

Lal-Nag M*, McGee L*, Titus SA, Brimacombe K, Michael S, Sittampalam G, Ferrer M. 2017. Exploring drug dosing regimens in vitro using real-time 3D spheroid tumor growth assays. SLAS Discov 22(5):537–546.
*Equal contributions