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Current Students

TME impact on epithelial tumorigenesis in NF1-deficient breast cancer.

Thesis project title to be determined

Thesis: Therapeutically targeting SWI/SNF mutant cancers

Thesis project title to be determined.

Thesis project title to be determined

Thesis: Investigating the roles of lysine-methyltransferases in the epigenetic regulation of cardiac and skeletal myogenesis

Thesis: Genetic modifiers of LRRK2-induced cellular toxicity

Thesis: Structural mechanisms of Wnt-mediated Frizzled activation

Thesis: Integrative approaches to structural biology

Thesis: Function study of MHC I in central neuronal system

Thesis project title to be determined

Thesis: Building a mitotic clock

Thesis project title to be determined

Thesis: A mechanistic approach to optimize mithramycin administration for the treatment of Ewing sarcoma

Thesis: Predicting response to kinase inhibitors in NF1-related malignancies based on tumor genomics

Thesis: Structural, biochemical and pharmacological analysis of TRP channels in chemosensation and signaling

Receptor specificity of Wnt signaling

Thesis project title to be determined

Thesis: Investigating RAS and RTK signaling in MPNST progression and drug resistance

Thesis project title to be determined

Thesis: Identification of trabectedin analogs that improve the suppression of EWS-FLI1

Thesis: Post-GWAS characterization of Parkinson’s disease risk-SNP rs356182

Thesis: Mechanisms of oncohistone-mediated tumorigenesis

Thesis: The role of polycomb target gene DNA methylation in intestinal tumorigenesis

Thesis: Epigenetic regulation through histone ubiquitination

Thesis: Identifying intramolecular and intermolecular interactions regulating LRRK2 activity and neurotoxicity