Current Students

Thesis project title to be determined

Thesis: TME impact on epithelial tumorigenesis in NF1-deficient breast cancer.

Thesis: Uncovering the functionality of PD risk-SNPs at the HLA locus in microglia

Thesis: Therapeutically targeting SWI/SNF mutant cancers

Thesis: Structural Basis of Regulation Mechanisms of TRPC3

Thesis: Investigating the mechanisms of LKB1-mediated inflammation in tumor progression

Thesis: Investigating the roles of lysine-methyltransferases in the epigenetic regulation of cardiac and skeletal myogenesis

Thesis: Structural mechanisms of Wnt-mediated Frizzled activation

Thesis: Genetic characterization of dementia in a Turkish cohort

Thesis: Investigating NF1 transcript variants in RAS deregulation and breast cancer progression

Thesis: Contributions of LRRK2 and alpha-synuclein in neuropathologic phenotypes of Parkinson’s disease

Thesis project title to be determined

Thesis: Building a mitotic clock

Thesis: Polysumoylation’s role in skeletal development and homeostasis

Thesis project title to be determined

Thesis: Structural, biochemical and pharmacological analysis of TRP channels in chemosensation and signaling

Thesis project title to be determined

Thesis: Receptor specificity of Wnt signaling

Thesis: Identification and exploitation of metabolic reprogramming in NF1-mutant breast cancer

Thesis project title to be determined

Thesis: Structure and repression mechanisms of plant MYC complexes: structural basis for MYC repressor-activator transition

Thesis: The role of the immune response in Parkinson’s Disease – a translational study in patients and model systems

Thesis: Defining molecular determinants of methyllysine-driven interactions

Thesis project title to be determined

Thesis project title to be determined

Thesis: Identifying pathways of therapy resistance in NF1-related MPNST

Thesis: Engineering stem cells to treat osteoarthritis

Thesis: Caloric restriction in mice increases the functionality of T cells, offsetting tumor burden

Thesis project title to be determined

Thesis: Post-GWAS characterization of Parkinson’s disease risk-SNP rs356182

Thesis: Linking glycosylation changes in Pancreatic Cancer with metabolic dependencies

Thesis: Impact of toxins and nutrients on brain function and development

Thesis: Deep molecular characterization of DNA methylation in human colorectal cancer

Thesis: Mechanisms of oncohistone-mediated tumorigenesis

Thesis: Identifying intramolecular and intermolecular interactions regulating LRRK2 activity and neurotoxicity